Featured Publications

The list below includes a selection of our publications highlighting our scientific output.


Hewick, R.M., M.W. Hunkapiller, L.E. Hood, and W.J. Dreyer A gas-liquid solid phase peptide and protein sequenator. J Biol Chem, 1981. 256(15): p. 7990-7. (PMID) (doi) (pdf)

Smith, L.M., J.Z. Sanders, R.J. Kaiser, P. Hughes, C. Dodd, C.R. Connell, C. Heiner, S.B. Kent, and L.E. Hood Fluorescence detection in automated DNA sequence analysis. Nature, 1986. 321(6071): p. 674-9. (PMID) (doi)

Ideker, T., T. Galitski, and L. Hood A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet, 2001. 2: p. 343-72. (PMID) (doi) (pdf)

Ideker, T., V. Thorsson, J.A. Ranish, R. Christmas, J. Buhler, J.K. Eng, R. Bumgarner, D.R. Goodlett, R. Aebersold, and L. Hood Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science, 2001. 292(5518): p. 929-34. (PMID) (doi) (pdf)

Geiss, G.K., R.E. Bumgarner, B. Birditt, T. Dahl, N. Dowidar, D.L. Dunaway, H.P. Fell, S. Ferree, R.D. George, T. Grogan, J.J. James, M. Maysuria, J.D. Mitton, P. Oliveri, J.L. Osborn, T. Peng, A.L. Ratcliffe, P.J. Webster, E.H. Davidson, L. Hood, and K. Dimitrov Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol, 2008. 26(3): p. 317-25. (PMID) (doi) (pdf)

Hwang, D., I.Y. Lee, H. Yoo, N. Gehlenborg, J.H. Cho, B. Petritis, D. Baxter, R. Pitstick, R. Young, D. Spicer, N.D. Price, J.G. Hohmann, S.J. Dearmond, G.A. Carlson, and L.E. Hood A systems approach to prion disease. Mol Syst Biol, 2009. 5: p. 252. (PMID) (doi) (pdf)

Chandrasekaran, S., and N.D. Price Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis. Proc Natl Acad Sci U S A, 2010. 107(41): p. 17845-17850. (PMID) (doi) (pdf)

Roach, J.C., G. Glusman, A.F. Smit, C.D. Huff, R. Hubley, P.T. Shannon, L. Rowen, K.P. Pant, N. Goodman, M. Bamshad, J. Shendure, R. Drmanac, L.B. Jorde, L. Hood, and D.J. Galas Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science, 2010. 328(5978): p. 636-9. (PMID) (doi) (pdf)

Ko, Y., S.A. Ament, J.A. Eddy, J. Caballero, J.C. Earls, L. Hood, and N.D. Price Cell type-specific genes show striking and distinct patterns of spatial expression in the mouse brain. Proc Natl Acad Sci U S A, 2013. 110(8): p. 3095-3100. (PMID) (doi) (pdf)

Hood, L. and N.D. Price Demystifying disease, democratizing health care. Sci Transl Med, 2014. 6(225): p. 225ed5. (PMID) (doi) (pdf)

Price, N.D., A.T. Magis, J.C. Earls, G. Glusman, R. Levy, C. Lausted, D.T. McDonald, U. Kusebauch, C.L. Moss, Y. Zhou, S. Qin, R.L. Moritz, K. Brogaard, G.S. Omenn, J.C. Lovejoy, and L. Hood A wellness study of 108 individuals using personal, dense, dynamic data clouds. Nat Biotechnol, 2017. 35(8): p. 747-756. (PMID) (doi) (pdf)

Bargaje, R., K. Trachana, M.N. Shelton, C.S. McGinnis, J.X. Zhou, C. Chadick, S. Cook, C. Cavanaugh, S. Huang, and L. Hood Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cells. Proc Natl Acad Sci U S A, 2017. 114(9): p. 2271-2276. (PMID) (doi) (pdf)

Kearney, P., J.J. Boniface, N.D. Price, and L. Hood The building blocks of successful translation of proteomics to the clinic. Curr Opin Biotechnol, 2018. 51: p. 123-129. (PMID) (doi) (pdf)

Hood, L.E., Lessons Learned as President of the Institute for Systems Biology (2000-2018). Genomics Proteomics Bioinformatics, 2018. 16(1): p. 1-9. (PMID) (doi) (pdf)