News

How Old Are You? Your Body Might Disagree With That Answer

Researchers at ISB harnessed deep molecular and physiological information to determine an individual’s biological age, which they found was reflective of overall health compared to chronological age. The findings were published in the Journals of Gerontology: Series A.

Using Blood to Predict Gut Microbiome Diversity

Predicting the alpha diversity of an individual’s gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.

Town Hall Seattle panel

Expert Panel Discusses 21st Century Health at Town Hall Seattle Event

In a public panel discussion put on by Town Hall Seattle and ISB, legendary biologist Dr. Lee Hood, PSJH Chief Clinical Officer Dr. Amy Compton-Phillips, and PATH’s Program Leader of Diagnostics Tala de los Santos addressed the promise — and challenges — of implementing and practicing 21st century health care.

Qiang Tian, MD, PhD

ISB’s Dr. Qiang Tian Joins Shanghai’s National Research Center for Translational Medicine

In the two decades since joining Dr. Lee Hood as a postdoc, Dr. Qiang Tian has made a tremendous impact on ISB’s science and culture. March 31 is his final day at ISB, as he is returning to China and joining Shanghai’s National Research Center for Translational Medicine.

Ozy’s ‘Future of X’ Podcast Features Drs. Jim Heath, Lee Hood

ISB President Dr. Jim Heath and ISB Co-founder Dr. Lee Hood are prominently featured in a new podcast created by Ozy, the popular news website. The podcast is called “The Future of X.” In the series’ first episode, Heath and Hood discuss cancer immunotherapy, personalized health care, and more.

Lee Hood at Visions of the Future

‘Visions of the Future’ Symposium Honors Dr. Lee Hood on his 80th Birthday

An impressive lineup of renowned researchers gathered at ISB recently for a one-day symposium, titled “Visions of the Future,” to honor ISB co-founder Dr. Lee Hood on his 80th birthday. Presenters included Drs. Irv Weissman, Ralph Snyderman, Ellen Rothenberg, Roger Perlmutter, Jim Heath, Trey Ideker, and more.

New ‘scientific wellness’ strategy could cut chronic illnesses and save money

“Scientific wellness” should be widely adopted as a health strategy to avoid chronic illnesses and reduce health care costs, said ISB co-founder Dr. Lee Hood, speaking at the “Schrödinger at 75 conference” on the future of biology, in Dublin. Hood’s presentation was covered by The Irish Times.

The Decades-Long Path That Led Philanthropist Carole Ellison to ISB

Philanthropist Carole Ellison created the recently unveiled K. Carole Ellison Fellows in Bioinformatics. “It’s so exciting to be part of (young researchers’) lives and help them along in their careers,” Ellison said.

ISB’s proteomics research in the spotlight

Microsoft Research recently deployed a video crew to come to ISB to speak with our researchers about proteomics and sharing peptide data. A story featuring the video was published on the Microsoft Research blog.

Turn Health Care Right-Side Up: Focus On Wellness Not Disease

“Another vision for health care is emerging — one that is focused on wellness rather than disease; one that is proactive instead of reactive; one that takes a systems approach to biology and medicine rather than studying one gene, one cell or one protein at a time.” Read this Psychology Today story penned by ISB’s Lee Hood and Nathan Price.

Dr. Jim Heath Takes Helm of ISB, Looks Toward the Future

Jim Heath took over as president of Institute for Systems Biology on January 1. To fully appreciate Heath’s relationship with ISB, you have to go back to its early days – shortly after the research organization was founded in 2000.

Key Strategies for Implementing Proteomics-Based Tests Across Disease States Highlighted in Current Opinion in Biotechnology

ISB, Integrated Diagnostics and Sera Prognostics just announced a paper entitled, “The building blocks of successful translation of proteomics to the clinic,” by Leroy Hood and colleagues published online in Current Opinion in Biotechnology.

Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s

Institute for Systems Biology (ISB) is among several organizations conducting a clinical trial testing how health coaching affects the cognitive function of patients with early-stage Alzheimer’s disease and analyzing longitudinal, multi-omic data to explore transitions in cognitive function over time.

High School Scientist Targets Sepsis, Earns $25,000 Scholarship Along the Way

Sriharshita Musunuri, 17, is looking to find and stop what causes sepsis, the top killer in American hospitals. She is collaborating with several ISB staff members, including mentor Chris Lausted, and just earned a $25,000 scholarship for her work.

Lessons I Learned from My 17 Years as ISB President

Lee Hood co-founded Institute for Systems Biology in 2000, and has served as president of the institution since; on January 1, 2018, he left that role to serve as chief science officer of Providence St. Joseph Health. Here, Hood shares the many lessons he learned from 17 years at the helm of ISB.

2017 Undergrad Interns

Summer 2017 brought a fresh cohort of undergraduate students interested in exploring ISB’s research in the Summer Undergraduate Research Experience Program. Each intern worked with a mentor on a research project and participated in learning experiences aimed at expanding his or her skills. Several of the interns worked in the group with mentors from the Hood-Price Lab. The ISB website has more details and a great collection of photos from…

ISB Annual Report: Catalyzing A Revolution

ISB’s compass has always been oriented toward the future. Even when we reflect on the past year for each annual report, it’s always through the lens of what’s on the horizon. We are remarkably consistent in that regard, which is in no small part due to our president Dr. Lee Hood, whose vision is perpetually a decade – at least – ahead of everyone else. In this year’s letter, Dr….

Our Artwork Featured On Cover of Nature Biotechnology

The Institute for Systems Biology and Arivale “Pioneer 100 Study” is featured on the cover of August’s Nature Biotechnology. The artwork was created by ISB’s Associate Director of Communications Allison Kudla in collaboration with contributing author John C. Earls, software engineer in the Hood-Price Lab. About the cover: A subset of statistically significant correlations are extruded in three-dimensional space. Price et al. describe the integration of whole genome sequences; clinical…