Feb. 27, 2017 ISB researchers and colleagues from several institutes published a new study today in Human Molecular Genetics. The key points of the study “High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds” are: A multi-institute collaboration mapped in high resolution the earliest effects of the Huntington’s disease mutation in mice. The study included four different genetic…
Read More‘Hyper Wellbeing’ is a summit to foster an emerging consumer technology industry. Consumer data-driven health, wellness and lifestyle optimization plus disease risk reduction. It represents a power shift towards the consumer and the future of mobile, wearables, health and wellness. Nathan Price presented at the Wellness as a Service World Summit, which took place on 14th November 2016 at the Computer History Museum (1401 N. Shoreline Blvd. Mountain View, CA…
Read MoreThe Institute for Systems Biology is a nonprofit biomedical research organization based in Seattle, Washington. It was founded in 2000 by systems biologist Leroy Hood, immunologist Alan Aderem, and protein chemist Ruedi Aebersold. ISB was established on the belief that the conventional models for exploring and funding breakthrough science have not caught up with the real potential of what is possible today. ISB serves as the ultimate environment where scientific…
Read MoreIt has been a year of milestones for the Wilke Cohen Lyme Disease Project. ISB received a transformational, multi-year pledge of $3 million from the Steven & Alexandra Cohen Foundation (read press release) and another magnanimous gift from Jeff and Liesl Wilke, who spearheaded the launch of the project in 2015. Our research team was also thrilled to be able to host Jeff and Liesl Wilke and Alex Cohen for…
Read MoreDr. Lee Hood, ISB president, and Nathan Price, ISB associate director, have joined the scientific advisory board of the newly launched Habit, which will begin to offer personalized nutrition plans based on your biology. From a recent Fast Company article: Neil Grimmer’s new startup, called Habit, aims to help others achieve their goals, whether it’s to lose weight or sleep more soundly. The company, which is launching in January, offers…
Read MoreNathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness.
Read MoreNIH Research Matters published an article on our tuberculosis paper. “The incredibly large number of possible drug combinations taken together with the difficulty of growing Mtb in the laboratory make discovery of effective combination therapy extremely challenging,” Dr. Nitin Baliga says. “We hope that our systems-based strategy will accelerate TB drug discovery by helping researchers prioritize combinations that are more likely to be effective.” READ THE ARTICLE
Read MorePRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…
Read MoreCongratulations to our colleague Dani Bergey in the Price Lab for receiving a Huntington’s Disease Society of America (HDSA) Donald A. King Summer Research Fellowship. “This is going to be a great step for her as she prepares to apply for graduate school next year,” said Nathan Price.
Read MoreISB is participating in The Seattle Foundation’s sixth annual GiveBIG day on May 3! And, this year, you can schedule your gift in advance. GiveBIG is an annual, community-wide day of giving hosted by The Seattle Foundation that aims to inspire regional philanthropy. Between midnight and midnight (PST) on May 3rd, The Seattle Foundation and its generous sponsors will match a percentage of all contributions to local nonprofits. GiveBIG 2015 raised…
Read MoreDr. Leroy Hood to serve as chief science officer for Providence FOR IMMEDIATE RELEASE SEATTLE – March 14, 2016 – With the goal of bringing personalized medicine to every patient, Providence Health & Services and the Institute for Systems Biology announced today an affiliation that will transform health care to a proactive mode that is focused on keeping patients well and identifying the earliest opportunities to reverse or even prevent…
Read MoreA 100k Wellness Project: A Data-Rich Longitudinal Study for the Digital Age was presented by Nathan Price, PhD at the Seattle Science Foundation‘s semi-monthly Spine Conference. Seattle Science Foundation is a non-profit organization dedicated to the international collaboration among physicians, scientists, technologists, engineers and educators. The Foundation’s training facilities and extensive internet connectivity have been designed to foster improvements in health care through professional medical education, training, creative dialogue and…
Read MoreIn a newly published research, former members of the Price lab Saheed Imam and Sascha Schäuble, in collaboration with the Baliga lab, share discoveries from their studies of Chlamydomonas reinhardtii – Chlamy for short. What follows is a short excerpt: To the casual observer, algae may appear to be a nuisance. But for researchers, photosynthetic microalgae and other microbes have the potential to become sustainable biofactories that can economically produce renewable…
Read MoreNathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness. Accessing the TLC 2015 videos requires a free subscription on the PLMI’s portal. Please register (for free) on this…
Read MoreISB Associate Director Dr. Nathan Price participated in the panel discussion “Revolutions in Healthcare: Impacts on the Future of the Food Industry” during the reThinkFood conference at The Culinary Institute of America in Napa Valley. The panelists each gave a short talk about his/her respective interests and then sat down to a discussion. It was an interesting intersection of perspectives from Kevin Slavin (MIT Media Lab), Molly Maloof (Physician Entrepreneur),…
Read MoreGeekwire.com announced its latest class of “Seattle 10” – the most innovative startups of the year. Arivale, a scientific wellness company that spun out of ISB’s 100K Wellness Project is one of the featured new companies. “This list showcases 10 of the most promising startup companies in the region— highlighting the very best and brightest.” Read about the Seattle 10…
Read MoreIn this presentation at the the Vancouver Bioinformatics Users Group from 2012, Nathan Price discusses approaches for the creation of quantitative systems models that can harness the power of genomics, by linking genotype to phenotype. The talk focuses particularly on automated methods for integrating metabolic and regulatory networks, such as Probabilistic Regulation of Metabolism (PROM) (Chandrasekaran and Price, PNAS, 2010). PROM is notable in that it represents the successful integration of a top-down reconstructed,…
Read MorePRESS RELEASE from Washington Research Foundation: Sept. 30, 2015, Seattle –– Washington Research Foundation (WRF), which supports groundbreaking technology in the life sciences, physical sciences and information sciences in Washington State, announced today that it will provide the Institute for Systems Biology (ISB) with $2 million in funding to bring increased research power to Seattle, and help place this community at the center of the coming transformation of the health…
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