Spotlight: Alison Paquette, Research Scientist
at the Institute for Systems Biology
News
Spotlight: Alison Paquette, Research Scientist
Congratulations to Alison Paquette who recently was promoted to Research Scientist in the Price Lab. Alison received her PhD in Experimental and Molecular Medicine at the Geisel School of Medicine at Dartmouth. She is interested in identifying molecular biomarkers that may predict preterm birth and adverse neonatal outcomes such as preeclampsia. “Pregnancy complications are not very well understood, and we are amongst the only labs really taking a systems biology…
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New Publication in Cell Systems
April 25, 2017 A Cell-Surface Membrane Protein Signature for Glioblastoma 3 bullets: Using integrated protein and gene expression data, ISB researchers developed a 33-gene signature for glioblastoma, an aggressive form of brain cancer. Glioblastoma gene signatures are associated with TGF-b signaling and cancer invasion. Researchers think that some of the glioblastoma gene signatures have the potential to be used as blood biomarkers for this aggressive cancer. Read the full summary…
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Institute for Systems Biology recruits technology pioneer James Heath as President
The Institute for Systems Biology has named James Heath, PhD, as its new president, effective January 2018. Heath is widely recognized as one of the world’s most accomplished scientists, working on fundamental problems at the interface of the chemical, physical, biological, and biomedical sciences, with focus areas of molecular biotechnologies and oncology. ISB’s co-founder and president Lee Hood, MD, PhD, was appointed senior vice president and chief science officer at…
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New Paper on Huntington’s Disease
Feb. 27, 2017 ISB researchers and colleagues from several institutes published a new study today in Human Molecular Genetics. The key points of the study “High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds” are: A multi-institute collaboration mapped in high resolution the earliest effects of the Huntington’s disease mutation in mice. The study included four different genetic…
Read MoreHow Scientific Wellness will drive the future of health
‘Hyper Wellbeing’ is a summit to foster an emerging consumer technology industry. Consumer data-driven health, wellness and lifestyle optimization plus disease risk reduction. It represents a power shift towards the consumer and the future of mobile, wearables, health and wellness. Nathan Price presented at the Wellness as a Service World Summit, which took place on 14th November 2016 at the Computer History Museum (1401 N. Shoreline Blvd. Mountain View, CA…
Read MoreNew video for the Institute for Systems Biology
The Institute for Systems Biology is a nonprofit biomedical research organization based in Seattle, Washington. It was founded in 2000 by systems biologist Leroy Hood, immunologist Alan Aderem, and protein chemist Ruedi Aebersold. ISB was established on the belief that the conventional models for exploring and funding breakthrough science have not caught up with the real potential of what is possible today. ISB serves as the ultimate environment where scientific…
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Wilke Cohen Lyme Disease Project Update & Site Visit
It has been a year of milestones for the Wilke Cohen Lyme Disease Project. ISB received a transformational, multi-year pledge of $3 million from the Steven & Alexandra Cohen Foundation (read press release) and another magnanimous gift from Jeff and Liesl Wilke, who spearheaded the launch of the project in 2015. Our research team was also thrilled to be able to host Jeff and Liesl Wilke and Alex Cohen for…
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Scientific Wellness Meets Personalized Nutrition
Dr. Lee Hood, ISB president, and Nathan Price, ISB associate director, have joined the scientific advisory board of the newly launched Habit, which will begin to offer personalized nutrition plans based on your biology. From a recent Fast Company article: Neil Grimmer’s new startup, called Habit, aims to help others achieve their goals, whether it’s to lose weight or sleep more soundly. The company, which is launching in January, offers…
Read More“Genomics, Big Data, Informatics and the Future of Medicine”: Nathan Price at the 2015 TLC
Nathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness.
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NIH Research Matters features ISB’s MTB paper
NIH Research Matters published an article on our tuberculosis paper. “The incredibly large number of possible drug combinations taken together with the difficulty of growing Mtb in the laboratory make discovery of effective combination therapy extremely challenging,” Dr. Nitin Baliga says. “We hope that our systems-based strategy will accelerate TB drug discovery by helping researchers prioritize combinations that are more likely to be effective.” READ THE ARTICLE
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Wilke Cohen Lyme Disease Project Receives $3M from the Steven & Alexandra Cohen Foundation
PRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…
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ISB Researcher Receives HDSA Fellowship
Congratulations to our colleague Dani Bergey in the Price Lab for receiving a Huntington’s Disease Society of America (HDSA) Donald A. King Summer Research Fellowship. “This is going to be a great step for her as she prepares to apply for graduate school next year,” said Nathan Price.
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GiveBIG on May 3 – or schedule your gift now!
ISB is participating in The Seattle Foundation’s sixth annual GiveBIG day on May 3! And, this year, you can schedule your gift in advance. GiveBIG is an annual, community-wide day of giving hosted by The Seattle Foundation that aims to inspire regional philanthropy. Between midnight and midnight (PST) on May 3rd, The Seattle Foundation and its generous sponsors will match a percentage of all contributions to local nonprofits. GiveBIG 2015 raised…
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Providence Health & Services and Institute for Systems Biology affiliate to catalyze scientific wellness
Dr. Leroy Hood to serve as chief science officer for Providence FOR IMMEDIATE RELEASE SEATTLE – March 14, 2016 – With the goal of bringing personalized medicine to every patient, Providence Health & Services and the Institute for Systems Biology announced today an affiliation that will transform health care to a proactive mode that is focused on keeping patients well and identifying the earliest opportunities to reverse or even prevent…
Read More“A 100k Wellness Project”, by Nathan Price
A 100k Wellness Project: A Data-Rich Longitudinal Study for the Digital Age was presented by Nathan Price, PhD at the Seattle Science Foundation‘s semi-monthly Spine Conference. Seattle Science Foundation is a non-profit organization dedicated to the international collaboration among physicians, scientists, technologists, engineers and educators. The Foundation’s training facilities and extensive internet connectivity have been designed to foster improvements in health care through professional medical education, training, creative dialogue and…
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Learning from microalgae as ‘biofactories’
In a newly published research, former members of the Price lab Saheed Imam and Sascha Schäuble, in collaboration with the Baliga lab, share discoveries from their studies of Chlamydomonas reinhardtii – Chlamy for short. What follows is a short excerpt: To the casual observer, algae may appear to be a nuisance. But for researchers, photosynthetic microalgae and other microbes have the potential to become sustainable biofactories that can economically produce renewable…
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Genomics, Big Data, Informatics and the Future of Medicine
Nathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness. Accessing the TLC 2015 videos requires a free subscription on the PLMI’s portal. Please register (for free) on this…
Read MoreScience, tech, design & food converge at reThinkFood conference
ISB Associate Director Dr. Nathan Price participated in the panel discussion “Revolutions in Healthcare: Impacts on the Future of the Food Industry” during the reThinkFood conference at The Culinary Institute of America in Napa Valley. The panelists each gave a short talk about his/her respective interests and then sat down to a discussion. It was an interesting intersection of perspectives from Kevin Slavin (MIT Media Lab), Molly Maloof (Physician Entrepreneur),…
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